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Ultrasound imaging drugs, particularly Definity made by Bristol-Myers Squibb and Optison from General Electric have drawn the attention of the FDA due to reports of deaths and serious cardiopulmonary reactions. These drugs are used to help doctors with difficult ultrasound tests that prove inconclusive in attempting to diagnose cardiac problems. The new black boxes will alert doctors to avoid using the drugs in patients with unstable angina, acute heart attacks, and unstable cardiopulmonary disease.

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